Lab News
2025
December 2025
Niki is awarded a Research Scholarship from the Hellenic Medical Society. Read more here. Congrats Niki!
Our work with the Gulko lab is published in Inflammation Research. Congrats to the whole team!
Laragione T, Dos Santos BG, Harris C, Goedeke L, Gulko PS. Arthritogenicity of CD11b + Gr1 + myeloid cells is dependent on dual specificity phosphatase 6 (DUSP6). Inflamm Res. 2025 Nov 11;74(1):162. doi: 10.1007/s00011-025-02134-0. PMID: 41217493.
October 2025
Niki is awarded the CSTP NIH/NHLBI T32- congrats!
August 2025
The Goedeke lab receives a second year of funding from the ES-DRC to continue studying cobalamin metabolism and steatotic liver disease
Connor is accepted into the MS in Nutrition and Metabolism Program at Boston University Chobanian & Avedisian School of Medicine with a Provost’s Scholarship. Congrats Connor!
July 2025
The Goedeke lab receives the Transformational Project Award from the American Heart Association to study the immunometabolic regulation of atherosclerosis by methylmalonic acid
Zoey joins the lab- welcome!
May 2025
Niki wins Best Basic Science Poster Award for her work on MMAB and cardiometabolic disease at the 3rd Annual Mount Sinai Fuster Heart Hospital Research Forum. Congrats!
April 2025
Leigh was selected as a finalist for the American Heart Association’s Irvine H. Page Junior Faculty Research Award
Linda joins the lab- welcome!
January 2025
Myles was recognized as a 2025 Regeneron STS Scholar (Semi-finalist in Cellular and Molecular Biology) for his work on the role of UBOX5 in regulating hepatic LDLR activity and cholesterol metabolism. Read more here. Congrats!
2024
December 2024
Myles is accepted into Cornell University College of Arts and Sciences. Congratulations!
Bernardo and Niki’s review article on mitochondrial uncouplers is published in Biochemical Journal
Dos Santos BG, Brisnovali NF, Goedeke L. Biochemical basis and therapeutic potential of mitochondrial uncoupling in cardiometabolic syndrome. Biochem J. 2024 Dec 4;481(23):1831-1854. doi: 10.1042/BCJ20240005. PMID: 39630236.
Our work on cardiac substrate utilization in heart failure is published in JCI.
Goedeke L, Ma Y, Gaspar RC, Nasiri A, Lee J, Zhang D, Galsgaard KD, Hu X, Zhang J, Guerrera N, Li X, LaMoia T, Hubbard BT, Haedersdal S, Wu X, Stack J, Dufour S, Butrico GM, Kahn M, Perry RJ, Cline GW, Young LH, Shulman GI. SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts. J Clin Invest. 2024 Dec 16;134(24):e176708. doi: 10.1172/JCI176708. PMID: 39680452; PMCID: PMC11645152.
with accompanying commentary:
Berger JH, Finck BN. Beyond ketosis: the search for the mechanism underlying SGLT2-inhibitor benefit continues. J Clin Invest. 2024 Dec 16;134(24):e187097. doi: 10.1172/JCI187097. PMID: 39680453; PMCID: PMC11645137.
November 2024
Niki and Connor’s short review article on resmetirom is published in Trends in Pharmacological Sciences
Brisnovali NF, Haney C, Goedeke L. Rezdiffra™ (resmetirom): a THR-β agonist for non-alcoholic steatohepatitis. Trends Pharmacol Sci. 2024 Nov;45(11):1081-1082. doi: 10.1016/j.tips.2024.08.009. Epub 2024 Sep 19. PMID: 39304473; PMCID: PMC11560534.
October 2024
Collaborative work with the Vatner lab is published in iScience. Congrats to the whole team!
Goedeke L, Strober JW, Suh R, Paolella LM, Li X, Rogers JC, Petersen MC, Nasiri AR, Casals G, Kahn M, Cline GW, Samuel VT, Shulman GI, Vatner DF. High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis. iScience. 2024 Oct 15;27(11):111175. doi: 10.1016/j.isci.2024.111175. PMID: 39524330; PMCID: PMC11550620.
May 2024
Niki and Bernardo are awarded ECR Travel Awards to present their work at the 4th Annual Immuno-metabolic Mechanisms in Atherosclerosis Fusion Conference in Mexico. Congrats!
April 2024
The Goedeke lab receives the ES-DRC Pilot & Feasibility Award (NIH/NIDDK) to study cobalamin metabolism and steatotic liver disease
March 2024
Myles wins second place in Cellular Biology at the 2024 New York State Science and Engineering Fair (NYSSEF) for his work on the role of UBOX5 in regulating cholesterol metabolism. Read more here. Congrats!
Niki wins Best Oral Presentation Award for her work on the CAD risk locus, MMAB/MVK, at the 2nd Annual Mount Sinai Fuster Heart Hospital Research Forum. Congrats!
2023
October 2023
Bernardo’s review article on macrophage immunometabolism is published
Gindri Dos Santos B, Goedeke L. Macrophage immunometabolism in diabetes-associated atherosclerosis. Immunometabolism (Cobham). 2023 Oct 16;5(4):e00032. doi: 10.1097/IN9.0000000000000032. PMID: 37849988; PMCID: PMC10578522.
September 2023
Niki wins Outstanding Poster Presentation Award at the 2nd Annual NYC Area Inter-Institutional Cardiovascular Research Retreat. Congrats!
July & August 2023
Connor joins the lab. Welcome!
Ephraim publishes his first co-author paper with our collaborator, Dr. Prashant Rajbhandari. Congrats to the whole team!
Patel S, Sparman NZR, Arneson D, Alvarsson A, Santos LC, Duesman SJ, Centonze A, Hathaway E, Ahn IS, Diamante G, Cely I, Cho CH, Talari NK, Rajbhandari AK, Goedeke L, Wang P, Butte AJ, Blanpain C, Chella Krishnan K, Lusis AJ, Stanley SA, Yang X, Rajbhandari P. Mammary duct luminal epithelium controls adipocyte thermogenic programme. Nature. 2023 Aug;620(7972):192-199. doi: 10.1038/s41586-023-06361-5. Epub 2023 Jul 26. PMID: 37495690.
June 2023
Members of the CVRI attend the Gordon Research Conference on Atherosclerosis in Spain. Leigh presents the lab’s work on the role of MMAB in regulating traditional atherosclerotic risk factors
March 2023
Weema and Niki are accepted into graduate school! Niki will be attending ISMMS and Weema will be attending Cornell- congrats!
Ephraim is accepted into medical school! He will be attending Hofstra University this fall- congrats!
January 2023
Bernardo and Myles join the lab— welcome!
2022
October 2022
Inaugural CVRI retreat
Niki joins the lab. Welcome Niki!
September 2022
Ephraim and Weema join the lab— welcome!
June 2022
The Goedeke Lab receives the Schneider-Lesser Foundation Fellowship for Junior Faculty to explore the role of a novel ubiquitin ligase in regulating hepatic LDLR expression and activity
The Seahorse XFe96 Analyzer arrives!
April 2022
Goedeke Lab officially opens